Indian scientists find a cure for IBD in pomegranate

Owing to a new research study led by the University of Louisville in the US Institute for Stem Cell Biology and Regenerative Medicine (inStem), of Bangalore, the pomegranate is said to possess proven benefits towards IBD and also provides protection against its onset.

IBD or Inflammatory Bowel Diseases refers to a series of illnesses whose onset can be traced back to the inflammation in the digestive tract. There exist two common types IBDs which are namely; the Ulcerative Colitis and Crohn’s Disease.

Being a chronic condition, IBD patients require treatment throughout their lives. Moreover, they have to continuously regulate their diets in order to be able to manage their condition.  However, the University of Louisville in the US Institute for Stem Cell Biology and Regenerative Medicine (inStem), of Bangalore have come up with a treatment to the condition. According to their research study, the Berries, fruits, and the tart cherries are a must have for the people suffering from IBD  Pomegranates are said to be the prime combat against this disease and are also proclaimed to provide protection against its onset.

Pomegranate is found to possess Urolithin A (UroA), which is a microbial metabolite and helps to reduce the IBD symptoms. Hence the people suffering from IBD should necessarily include the pomegranates in their diets.

More than a million people in the world are found to suffer from chronic intestinal inflammation which marks the onset of IBD in the body. It is mainly triggered by the presence of toxins which are leaked when the junction proteins present at the gut barrier are compromised. The Urolithin A not only helps to reduce the symptoms of IBD but also help to increase the proteins which tighten the single-cell epithelial layer and hence stop the gut inflammation.

However, the naturally occurring microbial metabolite in the pomegranates has a stability limitation, which the researchers think they can overcome by using a synthetic analog. This metabolite was only thought to help IBD patients, due to their anti-inflammatory effects.

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